Detecting polyps and lesions during colonoscopies

Left image: polyps annotated by experts; right image: polyps detected by AI
  • Colorectal cancer is the second most common cause of death from cancer for men and women alike.
  • In most cases, colonic polyps are symptomatic of the early stages of colorectal cancer.
  • Regular screening helps detect polyps at an early stage and thus prevent this type of cancer from developing.

 

Problem

Such polyps, however, are often missed during colonoscopies. Small polyps and flat new polyp formations that are deeply embedded are especially difficult to detect. And the physician’s experience and level of attention can also influence the detection rate.


Solution

Automatically detect and highlight polyps in the endoscope’s live video signal.  

The future of colonoscopy: AI-based polyp detection

Goal

Increase polyp detection sensitivity and specificity using artificial intelligence.

 

Current status

  • Built Multi-center, multi endoscope database
    •     “Bayreuth” DB: 2484 640 x 504 HD (no open access database!)
    •     Public dataset CVC-ClinicDB: 612 388 x 284 SD
    •     Public dataset ETIS-LaribPolypDB: 194 1225 x 966 HD
  • Trained Deep Neural Network to detect and outline polyps
  • Results for above datasets: recall of 83-92% and precision of 74-86%
  • Looking for commercialization partners

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Literature

Zobel et al, Computer Aided Detection of Polyps in Whitelight-Colonoscopy Images using Deep Neural Networks , Current Directions in Biomedical Engineering 2018;4(1)

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AI-free real-time detection

  • In 2017, our AI-free real-time detection software was used in a prospective study at the Klinikum rechts der Isar of the Technical University of Munich
  • Results        
    • The detection system was applied in 55 routine colonoscopies free of any complications
    • Our algorithm has detected 55 out of 73 (75%). All polyps exceeding 7mm have been correctly detected  
  • Conclusion
    • Computer-assisted automated low-delay polyp detection is feasible during real-time colonoscopy
    • The detection rate with respect to smaller and flat shaped polyps is currently being improved

 

Further information: Kolopol Research Project (finished)

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Literature

Gastrointest Endosc. 2019 Mar;89(3):576-582.e1. doi: 10.1016/j.gie.2018.09.042 Epub 2018 Oct 17, https://www.ncbi.nlm.nih.gov/pubmed/30342029
Klare et al., Automated polyp detection in the colorectum: a prospective study (with videos).

More Information

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