Fraunhofer Institute for Integrated Circuits IIS
Fraunhofer Institute for Integrated Circuits IIS
Biosignal analysis
© Fraunhofer IIS
Biosignal analysis - evaluation of electrochemical biosensors

Electrochemical biosensor evaluation

© Fraunhofer IIS

Electrochemical impedance spectroscopy for personalized medicine

Impedance spectroscopy
© Fraunhofer IIS

Impedance measurements can be used to detect the smallest changes in electrochemical systems. For example, tumor cells can be distinguished from healthy cells, pathological tissue changes can be detected and the reaction of cells to certain substances can be analyzed.

Among other things, this enables

  • early detection of diseases 
  • the creation of therapy plans according to individual tolerability and efficacy
  • better understanding of the (individual) mechanisms of action of the human organism

We are your development partner for electrochemical instrumentation

In order for biosensors to meet the requirements of the addressed use case and to be used successfully, factors such as reliability, size, power requirements and automation are of great relevance.

We build on your existing sensor front-end and develop electronics, firmware and software. Thus, you receive an innovative system for an energy-efficient and mobile sensor device – optimized for your specific sensor front-end for application outside the laboratory.

  • Electrochemical instrumentation of biosensors - miniaturized, energy-efficient, application-oriented
  • Continuous support from laboratory set-up to robust sensor device
  • Our combined knowledge from the fields of electrochemistry, medicine and engineering, to develop electronics, firmware and software for you

 

Elektrochemische Instrumentierung

Fraunhofer as develop partner

As your partner for the development of embedded systems, we accompany you on the way from the research lab to the real application.

Your advantages

  • Application-specific design and optimization of instrumentation
  • Automated and continuous data acquisition in the application environment
  • Long application life due to low energy consumption, short measurement times and efficient data analysis
  • Small installation space due to miniaturized electronics

Our offer:

Our offer

Example project: KardiaTool

Development and validation of a POCT device that allows the detection of cardiological biomarkers (cortisol, NT-ProBNP, TNF-a, IL-10) in saliva.

Objectives:

  • Early detection of heart failure by realizing a POCT device to detect cardiac biomarkers in saliva.
  • Non-invasive, rapid and quantitative detection of biomarkers
  • Software for data analysis and decision support

Development of instrumentation for:

  • Electrochemical impedance spectroscopy (4-channel) for field-effect transistor-based biosensors ("ImmunoFET").
  • Pneumatic interface for control of microfluidic valves & diaphragm pumps
  • Coil driver for interaction with magnetic nanoparticles (MNP)
  • Change of inductance by accumulation of MNP
  • Graphical user interface and HL7 communication to the cloud

Example project: Biosensor and PNT integration

Analysis of different groups of biosensors and investigation of integration potential for PNT (position, navigation & timing).

Project Content:

  • Identifying use cases for biosensors that can benefit from PNT integration.
  • Evaluation of use cases based on in-depth market and competitive analysis and design requirements
  • Preparation of a technical design on implementation and integration options, including system architecture and simulations

Example project: ELECSA

ELECSA – Electrolyte Sweat Analyzer: Mobile, energy-efficient evaluation electronics for thin-film sensors with ion-selective membrane

  • Integration of the measuring system into plasters and textiles by cooperation partners
  • Connection of the sensor system via Bluetooth
  • Non-invasive, continuous early detection of electrolyte disorders in premature infants
  • Reliable detection of ammonia in sweat

More information

Sensor Solutions for Healthcare and Medicine

Medical measurement technology – acquisition of biosignals and body functions

 

More about vital sensors

We bring Digital Medicine to the People

Digital Health Systems – Intelligent solutions for sensor technology and data analysis

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